Statins and Cholesterol

Share this & earn $10
Medicurio
Published at : 28 Dec 2020
161425 views
2314
162

Statins are one of the most highly prescribed and commercially successful drugs in modern society, due to their ability to decrease LDL-cholesterol and lower the risk of developing cardiovascular disease. Learn more about the history, mechanism, and side effects of statins in this episode of Medicurio.

Other lipoprotein particles:
You may have heard of LDL cholesterol as "bad" cholesterol because it clogs up the blood vessels with plaque. Its counterpart, HDL or "good" cholesterol does the opposite - HDL particles move throughout the bloodstream and pick up any cholesterol it finds and brings it back to the liver. Often times, plaque formation is dependent on both how much LDL and how little HDL there is in the blood.

Dr. Endo's story on his discovery of compactin: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108295/

CVD Risk Calculator by the American College of Cardiology: http://tools.acc.org/ASCVD-Risk-Estimator-Plus/

References:

Hajar R. Statins: Past and Present. Heart Views : The Official Journal of the Gulf Heart Association. 2011;12(3):121-127.

Thompson, P. D., Clarkson, P., Karas, R. H. (2003). Statin-associated myopathy. Journal of American Medical Association, 289(13): 1681-1690.

Golomb, B. A., & Evans, M. A. (2008). Statin Adverse Effects: A Review of the Literature and Evidence for a Mitochondrial Mechanism. American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions, 8(6), 373–418.
statinscholesterolLDL cholesterol

New excavator hammer

New excavator hammer

Tom Brady's Protein Routine

Tom Brady's Protein Routine

Hans Zimmer - Time (Inception)

Hans Zimmer - Time (Inception)

Kevin Zadai: The Next Move of God…is YOU

Kevin Zadai: The Next Move of God…is YOU

Five Ways to Immediately Improve Your Preaching

Five Ways to Immediately Improve Your Preaching

MSI's New Laptop Includes a 24 Million Color Light Show

MSI's New Laptop Includes a 24 Million Color Light Show

Men Need This Kind of Purpose To FULLY COMMIT To YOU

Men Need This Kind of Purpose To FULLY COMMIT To YOU

7 BROKEN Champions we DONT Want in Wild Rift (LoL Mobile)

7 BROKEN Champions we DONT Want in Wild Rift (LoL Mobile)

Very Beautyful And Impressive Bell Gown Paty Wear Baby Dresses Latest Designs

Very Beautyful And Impressive Bell Gown Paty Wear Baby Dresses Latest Designs

One is Laughing the Other Screaming. Bushman Prank

One is Laughing the Other Screaming. Bushman Prank

Psychiatrist: Trump Became The Same ‘Sadistic, Tyrannical And Cruel’ Person His Father Was | MSNBC

Psychiatrist: Trump Became The Same ‘Sadistic, Tyrannical And Cruel’ Person His Father Was | MSNBC

Cleopanthra | The Pink Panther (1993)

Cleopanthra | The Pink Panther (1993)

Health issues requiring an immediate emergency room visit - Penn State Health St. Joseph

Health issues requiring an immediate emergency room visit - Penn State Health St. Joseph

Marginal Propensity to Consume: the Wealthy and the Poor

Marginal Propensity to Consume: the Wealthy and the Poor

Asking questions in English | Use of How many| How much | How long | How often | English class

Asking questions in English | Use of How many| How much | How long | How often | English class

Growing concerns about people using steaming therapy to treat COVID-19

Growing concerns about people using steaming therapy to treat COVID-19

7 Details that Make or Break an Outfit - Tips for More Stylish Menswear Looks

7 Details that Make or Break an Outfit - Tips for More Stylish Menswear Looks

Don't Have Any Friends?

Don't Have Any Friends?

How to transform apocalypse fatigue into action on global warming | Per Espen Stoknes

How to transform apocalypse fatigue into action on global warming | Per Espen Stoknes

Karma Healing - How Past Life Karma Works

Karma Healing - How Past Life Karma Works

I AM WEALTHY - Powerful Affirmations To Manifest Abundance, Prosperity, Money, Mind Power

I AM WEALTHY - Powerful Affirmations To Manifest Abundance, Prosperity, Money, Mind Power

King's Quest 8 (30/39): The Barren Region (4/5)

King's Quest 8 (30/39): The Barren Region (4/5)

15 Things You Didn’t Know About the Illuminati

15 Things You Didn’t Know About the Illuminati

Bring Happiness Into Your Home | Mahatria Funny Speech

Bring Happiness Into Your Home | Mahatria Funny Speech

How It's Actually Made - Soy Sauce

How It's Actually Made - Soy Sauce

Latest mehndi dupatta/outfit designs|The Style Gorgeous

Latest mehndi dupatta/outfit designs|The Style Gorgeous

Top 20 Biggest Jumpscares Of 2020

Top 20 Biggest Jumpscares Of 2020

Alternate Universe Snacks Taste Test

Alternate Universe Snacks Taste Test

Stop Searching. Start Browsing. | Ancestry

Stop Searching. Start Browsing. | Ancestry

YEBBA - My Mind | Sofar NYC

YEBBA - My Mind | Sofar NYC

🇮🇲 Isle of Man TT TOP SPEED 🔥 Extremely Shock You 😱

🇮🇲 Isle of Man TT TOP SPEED 🔥 Extremely Shock You 😱

❤️ARIES "This Can Go Either Way But What Ever You Choose Watch This Before You Do!" JANUARY 2021

❤️ARIES "This Can Go Either Way But What Ever You Choose Watch This Before You Do!" JANUARY 2021

Energy balance is crucial to the indoor climate of your home

Energy balance is crucial to the indoor climate of your home

King County @ Your Service with Jackie Ablao

King County @ Your Service with Jackie Ablao

Vs Explosive Grey 3 hitter in 1st inning

Vs Explosive Grey 3 hitter in 1st inning

Rockstar's Error Allows You To Get Infinite Money In GTA 5 (Fact)

Rockstar's Error Allows You To Get Infinite Money In GTA 5 (Fact)

NHL: Cross Checking

NHL: Cross Checking

Use the LARGE function in Excel

Use the LARGE function in Excel

That one kid who thinks they are the smartest in their class bcuz they got a A- | gacha

That one kid who thinks they are the smartest in their class bcuz they got a A- | gacha

Historical Overview of Professional Counseling

Historical Overview of Professional Counseling

Norway | 1st place | Lahti | Team Large Hill | FIS Ski Jumping

Norway | 1st place | Lahti | Team Large Hill | FIS Ski Jumping

GTA 5 - Collecting FAMOUS FOOTBALLER Super Cars!

GTA 5 - Collecting FAMOUS FOOTBALLER Super Cars!

Letter A Logo Design on iPad Pro - Affinity Designer Tutorial

Letter A Logo Design on iPad Pro - Affinity Designer Tutorial

How to Bend a Soccer ball with the Outside of Your Foot | Tutorial

How to Bend a Soccer ball with the Outside of Your Foot | Tutorial

Verstappen & Ricciardo’s hilarious interview & Lewis Hamilton in the jungle🤣🌱 | At Home With Sky F1

Verstappen & Ricciardo’s hilarious interview & Lewis Hamilton in the jungle🤣🌱 | At Home With Sky F1

10 Winter FASHION TRENDS Worth Trying in 2021!

10 Winter FASHION TRENDS Worth Trying in 2021!

Top 25 Tips and Tricks for Microsoft Teams

Top 25 Tips and Tricks for Microsoft Teams

Google I/O 2013 - Cognitive Science and Design

Google I/O 2013 - Cognitive Science and Design

Air Climber Chapter 1 (just for personal use)

Air Climber Chapter 1 (just for personal use)